Expedited Therapeutic Outcomes for Habit Reversal Training for Youth with Chronic Tic Disorders

Grant Type
Clinical
Grant Year
2015-2016
Institution Location
CA
Institution Organization Name
University of California
Investigators Name
McGuire, Joseph Frank, PhD

Summary: Behavioral interventions, such as the Comprehensive Behavioral Intervention for Tics (CBIT) reduce the severity of tics. While many people who receive CBIT experience some benefit, only about half experience a clinically meaningful response. Recent research has identified several medications (called cognitive enhancers) that may increase the learning that occurs during treatments like CBIT to produce greater and/or accelerated improvement in symptoms. This study seeks to examine if one of these medications (called d-cycloserine, DCS) can accelerate improvements for children receiving behavior therapy. Joseph Frank McGuire, Ph.D. (anticipated July 2015); James McCracken, M.D.; John Piacentini, Ph.D. University of California, Los Angeles, CA; UCLA Semel Institute, Los Angeles, CA Award: $40,000 Tourette Association of America Inc. – Research Grant Award 2015-2016