HRT and ACT for Chronic Tic Disorders: A Pilot Project

Grant Type
Grant Year
Institution Location
Institution Organization Name
Duke University Medical Center
Investigators Name
Compton, Scott, PhD

Chronic tic disorders (CTD), including Tourette Syndrome, affect approximately 1 in 100 individuals and pediatric onset is the norm. Given that partial response to medication is common, there is a clear need to develop psychosocial treatments to enhance outcomes among youth with CTD. In this study we will develop a novel psychosocial intervention that combines habit reversal training (HRT) (also known as cognitivebehavioral treatment (CBT)) with Acceptance and Commitment Therapy (ACT) for teens and young adults with CTD, ages 12-17. First, our research teams will be trained in the delivery of HRT for CTD which will be pilot tested in 6 participants (3 at each site.) During this time, we will be developing a novel intervention that combines HRT with ACT. The novel HRT/ACT combined treatment will be pilot tested in six additional participants and results compared with the HRT. These activities will enable us to subsequently develop the cross-site clinical trails research infrastructure needed for future large-scale studies in which the efficacy of HRT and ACT/HRT can be compared directly, both with and without medication. Also, the mechanisms underlying the treatment effects can be examined. This research will improve knowledge about psychotherapy for tic disorders, which may yield broader improvements in treatment access and quality of care for those affected by TS. Scott N. Compton, Ph.D., Duke University Medical Center, Durham, North Carolina Martin E. Franklin, Ph.D., University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Award: $37,500 Tourette Association of America Inc. – Research Grant Award 2006-2007