Testing a Pathophysiological Model of Complex Tics

Grant Type
Grant Year
Institution Location
Institution Organization Name
Washington University School of Medicine
Investigators Name
Richards, Cheryl A., PhD

Summary: The underlying causes of tics are still unknown. We will examine to what extent somatic attention, such as focusing on physical sensations, and motor inhibition failure contribute to tics. We will study two groups of people: people with TS and people who do not have TS. We expect that people with TS will exhibit more brain activity when focusing on spontaneous physical sensations compared to the other subjects. We also expect that activity in certain brain regions will be associated with successful tic suppression by people with TS and successful eye blink suppression by people in both groups Cheryl A. Richards, Ph.D.; Kevin J. Black, M.D. Washington University, St. Louis, MO Award: $150,000 Tourette Association of America Inc. – Research Grant Award 2015-2016